Section 5.2 – Journal Club & Case Presentations

2018

DATE TOPIC SPEAKER
12/02/2018 Water D Marais
26/02/2018 Review on Toxic alcohols GF vd Watt
12/03/2018 Free Androgen Index/Testo Calculations J Cole
19/03/2018 Deep Learning in Medicine J Rusch
26/03/2018 CASE: Congenital Hyperinsulinism (Nesidioblastosis) D vd Westhuizen
23/04/2018 Munchausen syndrome and factitious disorder: the role of the lab in its detection and diagnosis C Hudson
14/05/2018 Renal Stones E Gantana
21/05/2018 UK Visit – Mitochondrial disorders S Meldau
28/05/2018 CASE:Two cases of hyperphosphataemic familial tumoral calcinosis caused by homozygous mutations in the GALNT3 gene. J Cole
29/05/2018 Plasma steroid metabolome for diagnosing and subtyping patients with Cushings C Hudson
11/06/2018 TB NanoDisk, MS-MS in TB diagnosis D vd Westhuizen
18/06/2018 Case Discussions and Feedback from LASSA H Vreede and D Marais
25/06/2018 Case – Hyperandrogenism R Dalmacio
23/07/2018 Apolipoprotein E: Update D Marais
13/08/2018 ZFN, TALEN, CRISPR – Genetic engineering D vd Westhuizen
20/08/2018 A phase-3 trial of L-glutamine in Sickle Cell Disease G vd Watt
27/08/2018 Organophosphate poisoning R Dalmacio
01/09/2018 Using Machine learning to aid the interpretation of urine steroid profiles C Hudson
22/10/2018 Network Medicine J Cole
15/10/2018 Imaging Mass Spectrometry J Pillay
29/10/2018 Hypercalcaemia: An Approach T Gcingca
01/11/2018 Lipoic Acid Biosynthesis Defects S Meldau
18/11/2018 Immune checkpoint inhibitors C Hudson

2019

DATE TOPIC SPEAKER(S)
11/02/2019 Snake envenomation D Marais
18/02/2019 Case presentation: R Banderker
25/02/2019 Metabolomics and mortality of naked mole rats. C Hudson
11/03/2019 Monitoring glycaemic control in individuals and populations H Vreede
18/03/2019 Cannabis in research R Dalmacio
08/04/2019 Between Chemistry and Genetics. Based on Carl Zimmer’s book She has her mother’s laugh D Marais
16/04/2019 Biomarkers in Schizophrenia J Lunn
29/4/2019 Disorders of Protein Folding D vd Westhuizen
13/05/2019 Unusual cases of metabolic disorders in 4 neonates G van der Watt
20/05/2019 Open Source Capillary Electrophoresis DJ vd Westhuizen
27/05/2019 Hypertriglycaeradimic pancreatitis TA Gcingca
03/06/2019 Journal Watch R Dalmacio, TA Gcingca, J Cole, J Lunn, DJ vd Westhuizen
20/06/2019 Short case presentations: DSD, Septic Cholestasis, SPE’s and their various presentations D vd Westhuizen, R Dalmacio, TA Gcingca
01/07/2019 Journal Watch R Dalmacio, TA Gcingca, J Cole, J Lunn, DJ vd Westhuizen
08/07/2019 Book Review Part 2: She Has Her Mother’s Laugh. Carl Zimmer AD Marais
22/07/2019 Flagger and Percentiler: A revolutionary EQA alternative C Hudson
29/07/2019 Case Presentation: A case of secondary hypogonadotrophic hypogonadism with Ecdysterone supplements DJ vd Westhuizen
05/08/2019 Journal Watch R Dalmacio, TA Gcingca, J Cole, J Lunn, DJ vd Westhuizen, J Rusch
12/08/2019 Nanobody development in Chemical Pathology TA Gcingca
19/08/2019 Book Review Part 2: She Has Her Mother’s Laugh. Carl Zimmer AD Marais
26/08/2019 Short case presentations: Macroprolactin and High dose hook effect; Urea Cycle defects in neonates at RXH TA Gcingca, JA Rusch
02/09/2019 Journal Watch R Dalmacio, TA Gcingca, J Cole, J Lunn
09/09/2019 Vaping vs. Smoking D Blackhurst
12/09/2019 Short case presentations: Insulin ; Globulin Gap J Cole, J Lunn
16/09/2019 Energy Metabolism – Micro-organisms metabolising lactate into Crebs Cycle intermediates G vd Watt
23/09/2019 Immunology overview R Dalmacio
30/09/2019 Meeting cancelled n/a
07/10/2019 Journal Watch D vd Westhuizen; TA Gcingca; R Dalmacio
10/10/2019 Short case presentations: Enzymology in reagents; A  case of cryoglobulinaemia TA Gcingca; D vd Westhuizen
07/11/2019 Short case: Methaemaglobinaemia R Dalmacio
11/11/2019 Microfluidics in Sweat Testing J Pillay
18/11/2019 Iron metabolism in microcytic hypochromic anaemia (Iron Lion Zion) J Rusch

2020

DATE TOPIC PRESENTER(S)
30-Mar-20 Case presentations:
Transient benign hyperphosphatasaemia; An approach to hyperandrogenism
T. Gcingca; M. Mahomed
20-Apr-20 Book review Part 3: She Has Her Mother’s Laugh. Carl Zimmer Prof D Marais
30-Apr-20 Case presentations 1) Electrolytes 2) Excess GH: Acromegaly D Roque, T. Gcingca
11-May-20 Excess GH: Acromegaly Part 2 T. Gcingca
18-May-20 Case Presentation: Hyperalbumineamia D. Roque
25-May-20 Case Presentations: OTC Case; Chylothorax from Thoracic injury R. Dalmacio, D. vd Westhuizen
08-Jun-20 Hyperammonaemia M. Mahomed
11-Jun-20 Case presentations:
A World of Colour;
A Lack of evidence is not evidence of absence
T. Gcingca, D. Roque
13-Jul-20 Quality assurance in clinical chemistry D. vd Westhuizen
20-Jul-20 EM Guidance, “Your future depends on your dreams so go to sleep” Kim Jacobs, J Rusch
27-Jul-20 Case presentations: MSc Project presentation; Porphyria cutanea tarda S. Lampert; T. Gcingca
17-Aug-20 Dyslipidemia R. Ateko
24-Aug-20 Anosmia/ Hyperosmia S. Meldau
31-Aug-20 Case presentations: CSF Leaks; CSF-IgG index M. Mahomed; C. Francis
14-Sept-20 DKA vs HHS T. Gcingca
21-Sept-20 Population genetics of the Indian Ocean humpback dolphin  (Honours project) S. Lampert
29-Sept-20 Case presentations: Methanol poisoning; COVID big data project  T. Gcingca; D. vd Westhuizen
19-Oct-20 Vitamin and homocysteine levels correlation with cardio metabolic risk factors K. Seakamela
26-Oct-20 Case presentations: Galactosaemia; Cryoglobulins M. Mahomed; C. Francis
11-Oct-20 Myeloma C. Francis
23-Nov-20 Case presentations:
Does this urine make me look fat? Lipiduria and fat embolism syndrome;
Critical results
M. Mahomed; R. Dalmacio
30-Nov-20 Machine learning D. vd Westhuizen

2021

DATE TOPIC PRESENTER(S)
08-Feb-21 Epigenetics and Diabetes J Rusch
15-Feb-21 Interference in Chemical Assays during COVID R. Dalmacio
22-Feb-21 Case Presentations: High testosterone in female (?) patient;
Hyponatremia with urine sodium measurement
T. Gcingca; D. vd Westhuizen
04-Mar-21 Case Presentations: Biochemical features of Pre-eclampsia;
Organophosphate poisoning
M. Mahomed; C. Francis
08-Mar-21 Green illness berfore the red carpet – Iron Metabolism D. vd Westhuizen
15-Mar-21 Malabsorption T. Gcingca
25-Mar-21 Supplemental nutrition C. Francis
29-Mar-21 Project presentations J. Pillay; R. Dalmacio; S. Lampert; S. Meldau; K. Khan
01-Apr-21 Insulin Sensitivity T. Gcingca
01-Apr-21 Project Presentations D. vd Westhuizen; C. Francis; M. Mahomed
15-Apr-21 Project presentation T. Gcingca
19-Apr-21 Fluorimetry C. Francis
26-Apr-21 Toxic Alcohol ingestion M. Mahomed
06-May-21 Persistent hypocalcemia D. vd Westhuizen
10-May-21 The Vital Question: Nick Lane D Marais

Journal Watch

We have a monthly meeting during which each attendant may briefly present relevant journal articles. Initially, it was left entirely up to the individual what they would present. However, from late in 2017, it was formalised the registrars’ contributions to ensure that the important journals were being covered. These include: Clinical Chemistry, Clinica Chimica Acta, Annals of Biochemistry, Clinics in Laboratory Medicine and Clinical Chemistry and Laboratory Medicine. Registrars are also encouraged to read NEJM, Nature, Cell, Science, The Lancet or any other journals of interest and to present what they feel is relevant. Each month we read and present several articles from at least one of these journals.

This was done on the first Monday of each month, after our departmental staff meeting. Dates are not recorded.